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Ayant droit économique

GlaxoSmithKline plc

3% threshold of purchase positions crossed down further to capital increase, as per publication in the Swiss Official Commercial Gazette (FOSC) on 17 October 2012. S.R. One, Limited, a Pennsylvania Business Trust, with its registered office at One Franklin Plaza, 200 N. 16th Street, Philadelphia, PA 19102, USA, and its business office at 161 Washington Street, Suite 500, Conshohocken, PA 18428 USA. Shares are held in record by S.R. One, Limited, a wholly-owned subsidiary of GlaxoSmithKline LLC. GlaxoSmithKline LLC is a company incorporated under the laws of the United States, with its registered office at Corporation Service Company, 2711 Centerville Road, Suite 400, Wilmington, Delaware 19808, USA, (a wholly-owned subsidiary of GlaxoSmithKline Holdings (Americas) Inc.). GlaxoSmithKline Holdings (Americas) Inc. is a company incorporated under the laws of the United States, with its registered office at Wilmington Trust SP Services Inc., 1105 North Market Street, Suite 1300, Wilmington Delaware 19801 USA, (a wholly-owned subsidiary of GlaxoSmithKline Finance plc). GlaxoSmithKline Finance plc is a company incorporated under the laws of England and Wales, with its registered office at 980 Great West Road, Brentford, Middlesex, TW8 9GS, United Kingdom (a wholly-owned subsidiary of GlaxoSmithKline Holdings Limited). GlaxoSmithKline Holdings Limited is a company incorporated under the laws of England and Wales, with its registered office at 980 Great West Road, Brentford, Middlesex, TW8 9GS, United Kingdom (a wholly-owned subsidiary of GlaxoSmithKline plc). GlaxoSmithKline plc with registered office and head office at 980 Great West Road, Brentford, Middlesex, TW8 9GS, United Kingdom (as beneficial owner).