Register of management transactions and significant shareholdings — Page 9

Idorsia Ltd

UBS Group AG · Single shareholder

Idorsia Ltd

The Goldman Sachs Group, Inc · Single shareholder

Perrot Duval Holding SA

Non-executive member of the board of directors · Registered shares

EFG International

Non-executive member of the board of directors · Registered shares

Emmi AG

Non-executive member of the board of directors · Registered shares

Swissquote Group Holding Ltd

BlackRock, Inc · Single shareholder

Swiss Prime Site AG

2 people · Dimensional Ireland Limited…

Kühne + Nagel International AG

BlackRock, Inc · Single shareholder

Helvetia Baloise Holding AG

Executive member of the board of directors / senior management · Registered shares

SMG Swiss Marketplace Group Holding AG

Executive member of the board of directors / senior management · Registered shares

St.Galler Kantonalbank AG

Executive member of the board of directors / senior management · Registered shares

Hypothekarbank Lenzburg AG

Non-executive member of the board of directors · Registered shares

Perrot Duval Holding SA

Non-executive member of the board of directors · Registered shares

Hypothekarbank Lenzburg AG

Non-executive member of the board of directors · Registered shares

Interroll Holding AG

Non-executive member of the board of directors · Registered shares

Walliser Kantonalbank

Executive member of the board of directors / senior management · Registered shares

VZ Holding AG

Executive member of the board of directors / senior management · Registered shares

Swissquote Group Holding Ltd

BlackRock, Inc · Single shareholder

Julius Bär Gruppe AG

Swisscanto Fondsleitung AG · Collective investment vehicle

DKSH Holding AG

BlackRock, Inc · Single shareholder

Swissquote Group Holding Ltd

BlackRock, Inc · Single shareholder

Swissquote Group Holding Ltd

BlackRock, Inc · Single shareholder